COX-2 Cybersomatic Optimizer

COX-2 Cybersomatic Optimizer

Class	Frontal Cortex
Tier	Iconic
Attribute	Intelligence
Capacity	50
Location	Dogtown

The COX-2 Cybersomatic Optimizer lets V's quickhacks land critical hits, and at its highest tiers nearly every one does. It is the Iconic variant of the Bioconductor, with a far higher Crit Chance. The price is a cut to max RAM and a heavy capacity cost. Netrunners who kill with Combat quickhacks gain the most. Guides rate it very highly for any build that relies on damaging quickhacks. The COX-2 Cybersomatic Optimizer is a mid to late game Phantom Liberty implant, sold by the ripperdocs in Dogtown and found in Dogtown airdrops.

Effect

The COX-2 is a passive Frontal Cortex implant. It unlocks critical hits for quickhacks, so every damaging quickhack rolls for one. The implant adds a very large Crit Chance for quickhacks, which reaches a sure critical hit at Tier 5. Combat quickhacks such as Short Circuit and Synapse Burnout benefit directly.

The drawback is a lower max RAM. Fewer RAM units means fewer quickhacks before V must wait for RAM to recover. The plus steps of Tier 5 shrink this penalty. At Tier 5++ the RAM cut is half of what it is at Tier 3.

The implant is attuned to Intelligence. Each Intelligence point adds a little quickhack damage, so a full Intelligence build gets the most from it. Its extra stat bonuses also suit a netrunner. The first bonus raises Reload Speed. Quickhack Damage arrives at Tier 2 and higher. RAM Regen from neutralizing an enemy needs the Driver Update perk.

How to Get COX-2 Cybersomatic Optimizer Guide

Install Phantom Liberty and reach Dogtown.
Visit a ripperdoc in Dogtown from level 20 to buy it at Tier 3.
Return at level 30 for Tier 4 and at level 40 for Tier 5.
Loot it from an airdrop cache in Dogtown, marked by red smoke.

COX-2 Cybersomatic Optimizer Map Location

COX-2 Cybersomatic Optimizer map location:

Map credit by Map Genie.

Upgrades

The COX-2 comes in Tiers 3, 4 and 5, with plus steps in between. The main tiers raise Crit Chance with quickhacks. The plus steps of Tier 5 reduce the max RAM penalty instead. The capacity cost stays the same at every tier, and it is very heavy. A ripperdoc can upgrade it with crafting components, which is the only way to reach Tier 5++. Cyberware Capacity Shards and the Edgerunner perk help make room for it.

The table shows what each tier step of COX-2 Cybersomatic Optimizer costs at a ripperdoc.

Upgrade	Components	Requirement
Tier 3 to Tier 3+	50 Tier 3 components	-
Tier 3+ to Tier 4	37 Tier 4 components	-
Tier 4 to Tier 4+	50 Tier 4 components	-
Tier 4+ to Tier 5	37 Tier 5 components	-
Tier 5 to Tier 5+	50 Tier 5 components	-
Tier 5+ to Tier 5++	125 Tier 5 components	Phantom Liberty

Character Builds

The COX-2 belongs in an Intelligence build that kills with quickhacks. Synapse Burnout deals more damage for each RAM unit already spent, and a critical hit makes that finishing blow far stronger. Overclock lets V keep hacking with too little RAM by paying Health, which softens the RAM penalty during a fight. Hack Queue and Queue Acceleration each add max RAM. Optimization raises RAM recovery.

The RAM Reallocator pairs well, because it adds max RAM and refills RAM when it runs low. The Tetratronic Rippler adds max RAM at Tier 4 and higher. A cyberdeck with many quickhack slots lets V carry several damaging quickhacks to make use of the critical hits.

Select a Build

Monowire BuildNetrunner BuildLucy Build

The Monowire whips several enemies at once from a short distance, and quickhacks are uploaded between attacks. Intelligence perks give the Monowire more damage and return RAM on hits. Overclock spends Health in place of RAM when a fight drags on.

Attributes: Body 15, Reflexes 20, Technical Ability 11, Intelligence 20, Cool 15.

The perks, cyberware and weapon mods for this build are listed below.

PerksCyberware

Name	Level	Effect
Comeback Kid	Body 4	Faster Health regeneration at low Health
Painkiller	Body 4	Slow Health regeneration in combat
Adrenaline Rush	Body 15	More Health and the Adrenaline Rush mode
Calm Mind	Body 15	Adrenaline lasts longer before it decays
Juggernaut	Body 15	More speed and damage during Adrenaline Rush
Eye In The Sky	Intelligence 4	Highlights cameras and makes camera quickhacks cheaper
Optimization	Intelligence 4	Faster RAM recovery
Copy-Paste	Intelligence 9	Quickhacks on an enemy netrunner spread to their allies
Counter-A-Hack	Intelligence 9	Counter quickhacks on enemy netrunners through walls
Embedded Exploit	Intelligence 9	Quickhacks hit harder on controlled enemies
Feedback Loop	Intelligence 9	Faster RAM recovery for each queued quickhack
Hack Queue	Intelligence 9	Queue two quickhacks on one enemy
Icepick	Intelligence 9	Cheaper Combat quickhacks on distracted or controlled enemies
Siphon	Intelligence 9	Monowire hits recover RAM
Finisher: Live Wire	Intelligence 15	A Monowire Finisher that restores Health and RAM
Overclock	Intelligence 15	More quickhack damage and the Overclock mode
Queue Acceleration	Intelligence 15	More RAM and cheaper device quickhacks
Queue Prioritization	Intelligence 15	Faster upload for the first quickhack in a queue
Sublimation	Intelligence 15	RAM recovery heals during Overclock
Queue Mastery	Intelligence 20	A longer quickhack queue that can be locked
Spillover	Intelligence 20	Quickhacks spread during Overclock
Parkour!	Reflexes 4	Faster climbing and vaulting
Slippery	Reflexes 4	Harder to hit while moving fast
Can't Touch This	Reflexes 9	Full Mitigation Chance while Dashing
Dash	Reflexes 9	Dash replaces the dodge
Data Tunneling	Relic	Monowire hits spread an uploaded quickhack to other enemies
Emergency Cloaking	Relic	Optical Camo can break enemy tracking in combat
Jailbreak	Relic	New abilities for every Arms cyberware
Vulnerability Analytics	Relic	Hits on enemy Vulnerabilities always crit
First Aid	Technical Ability 4	Faster Health item recharge after one use
Glutton For War	Technical Ability 4	Kills recharge Health items and grenades
Transfusion	Technical Ability 4	More Health from the last Health item charge
All Things Cyber	Technical Ability 9	Stronger cyberware stats
Health Freak	Technical Ability 9	One more Health item charge and faster recharge
Renaissance Punk	Technical Ability 9	More cyberware capacity for each attribute at 9 or higher

Name	Slot	Effect
Monowire	Arms	Arm whip that hits several enemies from a distance
Thermal Monowire	Arms	Monowire that deals Thermal damage and can burn
Heal-On-Kill	Circulatory System	Health on each kill
Kiroshi Cockatrice Optics	Face	More crit chance
Kiroshi Sentry Optics	Face	Scanning highlights cameras and turrets
Bioconductor	Frontal Cortex	Quickhacks can deal critical hits
Optical Camo	Integumentary System	Near invisibility for a few seconds
Pain Editor	Integumentary System	Less damage taken
Subdermal Armor	Integumentary System	More armor
Reinforced Tendons	Legs	Double jump
Adrenaline Converter	Nervous System	Faster movement when combat starts
Militech Paraline	Operating System	Cyberdeck with Smart weapon bonuses
Dense Marrow	Skeleton	More melee damage for a higher Stamina cost

Quickhacks do most of the damage, chained from cover before enemies find the character. The Tetratronic Rippler cyberdeck adds quickhack damage, and Overclock spends Health in place of RAM. A smart weapon or the Monowire finishes anyone left standing.

Attributes: Body 16, Reflexes 15, Technical Ability 15, Intelligence 20, Cool 15.

The perks, cyberware and weapon mods for this build are listed below.

PerksCyberware

Name	Level	Effect
Painkiller	Body 4	Slow Health regeneration in combat
Adrenaline Rush	Body 15	More Health and the Adrenaline Rush mode
Calm Mind	Body 15	Adrenaline lasts longer before it decays
Juggernaut	Body 15	More speed and damage during Adrenaline Rush
Acquisition Specialist	Intelligence	Wider Smart reticle and lock kept through reloads
Encryption	Intelligence 4	Quickhacks are harder to trace
Eye In The Sky	Intelligence 4	Highlights cameras and makes camera quickhacks cheaper
Optimization	Intelligence 4	Faster RAM recovery
Proximate Propagation	Intelligence 4	Cheaper quickhacks at close range
Subordination	Intelligence 4	Control quickhacks last longer on enemies at full Health
Warning: Explosion Hazard	Intelligence 4	Stronger explosions from hacked devices
Counter-A-Hack	Intelligence 9	Counter quickhacks on enemy netrunners through walls
Data Recycler	Intelligence 9	RAM back from queued quickhacks after a kill
Embedded Exploit	Intelligence 9	Quickhacks hit harder on controlled enemies
Feedback Loop	Intelligence 9	Faster RAM recovery for each queued quickhack
Hack Queue	Intelligence 9	Queue two quickhacks on one enemy
Icepick	Intelligence 9	Cheaper Combat quickhacks on distracted or controlled enemies
Precision Subroutines	Intelligence 9	Smart weapon accuracy scales with max RAM
Recirculation	Intelligence 9	Smart weapon kills restore RAM
Siphon	Intelligence 9	Monowire hits recover RAM
Speculation	Intelligence 9	Combat quickhack kills recover RAM
System Overwhelm	Intelligence 9	More quickhack damage for each effect on the target
Blood Daemon	Intelligence 15	Health back for each queued quickhack on a kill during Overclock
Overclock	Intelligence 15	More quickhack damage and the Overclock mode
Power Surge	Intelligence 15	Overclock heals on activation
Queue Acceleration	Intelligence 15	More RAM and cheaper device quickhacks
Queue Prioritization	Intelligence 15	Faster upload for the first quickhack in a queue
Race Against Mind	Intelligence 15	More quickhack damage at lower Health during Overclock
Sublimation	Intelligence 15	RAM recovery heals during Overclock
Target Lock Transfer	Intelligence 15	Wider Smart reticle and locks kept on swap
Queue Mastery	Intelligence 20	A longer quickhack queue that can be locked
Smart Synergy	Intelligence 20	Instant lock and more damage during Overclock
Spillover	Intelligence 20	Quickhacks spread during Overclock
Slippery	Reflexes 4	Harder to hit while moving fast
Dash	Reflexes 9	Dash replaces the dodge
Air Dash	Reflexes 15	Dash in midair
Emergency Cloaking	Relic	Optical Camo can break enemy tracking in combat
Machine Learning	Relic	Crit damage builds on enemy Vulnerabilities
Vulnerability Analytics	Relic	Hits on enemy Vulnerabilities always crit
Glutton For War	Technical Ability 4	Kills recharge Health items and grenades
All Things Cyber	Technical Ability 9	Stronger cyberware stats
Chipware Connoisseur	Technical Ability 9	A choice of stat bonus when upgrading cyberware
Driver Update	Technical Ability 9	An extra stat bonus on every cyberware
Renaissance Punk	Technical Ability 9	More cyberware capacity for each attribute at 9 or higher
Extended Warranty	Technical Ability 15	Cyberware effects last longer
License To Chrome	Technical Ability 15	Stronger cyberware, more armor and a Skeleton slot

Name	Slot	Effect
Monowire	Arms	Arm whip that hits several enemies from a distance
Thermal Monowire	Arms	Monowire that deals Thermal damage and can burn
Heal-On-Kill	Circulatory System	Health on each kill
Kiroshi Sentry Optics	Face	Scanning highlights cameras and turrets
Ex-Disk	Frontal Cortex	More max RAM and faster uploads
Smart Link	Hands	Turns on Smart weapon tracking
Optical Camo	Integumentary System	Near invisibility for a few seconds
Reinforced Tendons	Legs	Double jump
Kerenzikov	Nervous System	Slows time when aiming during a slide or dodge
Tetratronic Rippler	Operating System	Cyberdeck that raises quickhack and weapon damage
RAM Recoup	Skeleton	Damage taken restores RAM

Modelled on Lucy from the anime, the build mixes quickhacks with the Monowire. Quickhacks spread through groups, then Monowire hits finish the weakened enemies. A power pistol covers enemies at range.

Attributes: Body 18, Reflexes 20, Technical Ability 3, Intelligence 20, Cool 20.

The perks, cyberware and weapon mods for this build are listed below.

PerksCyberware

Name	Level	Effect
Comeback Kid	Body 4	Faster Health regeneration at low Health
Painkiller	Body 4	Slow Health regeneration in combat
Adrenaline Rush	Body 15	More Health and the Adrenaline Rush mode
Calm Mind	Body 15	Adrenaline lasts longer before it decays
Juggernaut	Body 15	More speed and damage during Adrenaline Rush
Eye In The Sky	Intelligence 4	Highlights cameras and makes camera quickhacks cheaper
Optimization	Intelligence 4	Faster RAM recovery
Warning: Explosion Hazard	Intelligence 4	Stronger explosions from hacked devices
Copy-Paste	Intelligence 9	Quickhacks on an enemy netrunner spread to their allies
Counter-A-Hack	Intelligence 9	Counter quickhacks on enemy netrunners through walls
Data Recycler	Intelligence 9	RAM back from queued quickhacks after a kill
Embedded Exploit	Intelligence 9	Quickhacks hit harder on controlled enemies
Feedback Loop	Intelligence 9	Faster RAM recovery for each queued quickhack
Hack Queue	Intelligence 9	Queue two quickhacks on one enemy
Icepick	Intelligence 9	Cheaper Combat quickhacks on distracted or controlled enemies
Siphon	Intelligence 9	Monowire hits recover RAM
Blood Daemon	Intelligence 15	Health back for each queued quickhack on a kill during Overclock
Finisher: Live Wire	Intelligence 15	A Monowire Finisher that restores Health and RAM
Overclock	Intelligence 15	More quickhack damage and the Overclock mode
Queue Acceleration	Intelligence 15	More RAM and cheaper device quickhacks
Queue Prioritization	Intelligence 15	Faster upload for the first quickhack in a queue
Race Against Mind	Intelligence 15	More quickhack damage at lower Health during Overclock
Sublimation	Intelligence 15	RAM recovery heals during Overclock
Queue Mastery	Intelligence 20	A longer quickhack queue that can be locked
Spillover	Intelligence 20	Quickhacks spread during Overclock
Slippery	Reflexes 4	Harder to hit while moving fast
Dash	Reflexes 9	Dash replaces the dodge
Air Dash	Reflexes 15	Dash in midair
Data Tunneling	Relic	Monowire hits spread an uploaded quickhack to other enemies
Jailbreak	Relic	New abilities for every Arms cyberware
Machine Learning	Relic	Crit damage builds on enemy Vulnerabilities
Vulnerability Analytics	Relic	Hits on enemy Vulnerabilities always crit
Edgerunner	Technical Ability 20	Cyberware past the capacity limit for a small Health cost

Name	Slot	Effect
Monowire	Arms	Arm whip that hits several enemies from a distance
Kiroshi Sentry Optics	Face	Scanning highlights cameras and turrets
Camillo RAM Manager	Frontal Cortex	Restores RAM when it runs low
Subdermal Armor	Integumentary System	More armor
Reinforced Tendons	Legs	Double jump
Militech Paraline	Operating System	Cyberdeck with Smart weapon bonuses
Dense Marrow	Skeleton	More melee damage for a higher Stamina cost

Lore

The COX-2 shares its in-game description with the Bioconductor. The text says it improves superconductivity in the circuits that connect the body's cyberware. In play, that means V's hacks hit with the same critical force as V's weapons. It is one of the Iconic implants that arrived with Phantom Liberty and are sold only inside Dogtown.