Neurotoxin Knife
| Neurotoxin Knife | |
|---|---|
 | |
| Class | Melee Weapon |
| Type | Throwable |
| Weapon | Knife |
| Headshot | +150% |
The Neurotoxin Knife is a throwable combat knife with a sharp edge and a dose of poison. Its in-game line calls it a deadly combination of physical and chemical damage. Each hit can poison the target and lowers its resistance to chemical damage. The knife gets more dangerous the longer a fight goes. It works best in a Cool build with the poison perks for thrown weapons. It is the base blade for the Iconic knife Blue Fang. Coach Fred's melee shop in Little China sells the Neurotoxin Knife early in the story, and enemies drop it later on.
Combat
The Neurotoxin Knife can be used in the hand or thrown. A thrown knife returns to V on its own after its recovery time. Its hits have a chance to poison the target. Each hit also lowers the target's chemical resistance for a while. These effects stack, so repeated cuts make every later hit of chemical damage hurt more.
Several Cool perks make poison stronger. Scorpion Sting adds poison to thrown crits, headshots and weak-spot hits. The Neurotoxin perk blinds poisoned enemies and stops them from sprinting. Accelerated Toxin Absorption makes a strong attack or a throw against a poisoned enemy deal a large burst of poison damage at once. Corrosion even lets the knife poison drones, robots, mechs and turrets.
The stacking resistance loss rewards staying on one tough enemy. The first hits poison the target. Every hit after that lands on a target with lower chemical resistance.
How to Get Neurotoxin Knife Guide
- Buy the Neurotoxin Knife from Coach Fred in Little China or another melee weapon seller.
- Loot it from enemies who carry one.
- Buy the crafting spec from a melee weapon seller and craft it.
Neurotoxin Knife Map Location
The map shows Coach Fred's melee weapon shop in Little China.
Neurotoxin Knife map location:
Map credit by Map Genie.
Compatible Mods
8 weapon mods are compatible with Neurotoxin Knife.
| Name | Image | Effect |
|---|---|---|
| Airstrike | 
|
Raises crit chance and crit damage for midair attacks |
| Boomerang | 
|
A headshot kill with a thrown weapon can return it at once |
| Cyclone | 
|
A sprint attack opens unlimited combos with stacking attack speed |
| Javelin | 
|
More armor penetration with melee, doubled on throws |
| Pax | 
|
Makes the weapon non-lethal, more damage outside combat |
| Severance | 
|
Hits to the head or limbs of a weakened enemy can dismember and kill |
| Silencio | 
|
More crit chance and crit damage when crouched and undetected |
| Zero-G | 
|
More effective range, thrown weapons fly straight |
Crafting Spec
Melee weapon vendors sell the Neurotoxin Knife spec. The spec lets V craft Neurotoxin Knife in the crafting menu. Every spec in the game is listed on the Crafting Specs page.
The table shows what crafting Neurotoxin Knife costs at each tier.
| Tier | Components |
|---|---|
| Tier 1 | 30 Tier 1 components |
| Tier 2 | 30 Tier 2 components |
| Tier 3 | 30 Tier 3 components |
| Tier 4 | 30 Tier 4 components |
| Tier 5 | 30 Tier 5 components |
Upgrades
Only Iconic weapons can be upgraded, so a stronger Neurotoxin Knife is a higher-tier one. Shops and loot rise with V's level. A crafted knife matches a bought one of the same tier. The crafting spec lets V turn crafting components into a new knife at the current tier.
Character Builds
The Cool tree holds the throwing perks. Scorpion Sting shortens throw recovery and adds poison on crits and headshots. Neurotoxin, Corrosion and Accelerated Toxin Absorption all branch from it and make poison stronger. Juggler cuts recovery further. It also resets throwable cooldowns after a thrown headshot or crit kill. Pay It Forward boosts the next throw after a knife is recovered from an enemy. Style Over Substance makes throws during a slide, dodge or crouch-sprint guaranteed crits. Finisher: Act Of Mercy adds a finisher for knives and axes that restores Health.
For cyberware, Handle Wrap adds crit chance with throwables after each throw. Stabber adds crit chance with blades and throwables. Its mod slots take throwable and blade mods. Boomerang gives the knife a chance to come straight back after a headshot kill. Javelin adds armor penetration, and the bonus doubles on throws. Haemocide makes Bleeding last longer and adds crit chance, but it lowers base damage a little.
Select a Build
The build opens from stealth and removes a few targets before the fight starts. Headshots and crits with thrown knives bring the knife back to hand through Juggler. When the character is detected, the Sandevistan or Kerenzikov slows time to finish the enemies who spotted it.
Attributes: Body 18, Reflexes 20, Technical Ability 20, Intelligence 3, Cool 20.
The perks, cyberware and weapon mods for this build are listed below.
| Name | Image | Level | Effect |
|---|---|---|---|
| Painkiller | 
|
Body 4 | Slow Health regeneration in combat |
| Adrenaline Rush | 
|
Body 15 | More Health and the Adrenaline Rush mode |
| Feline Footwork | 
|
Cool 4 | Faster and safer while crouched |
| Killer Instinct | 
|
Cool 4 | More damage with knives, axes and silenced guns before combat |
| Gag Order | 
|
Cool 4 | A quick hit after being spotted delays detection by others |
| Scorpion Sting | 
|
Cool 9 | Thrown crits and headshots apply Poison |
| Neurotoxin | 
|
Cool 9 | Poison also blinds and stops sprinting |
| Parasite | 
|
Cool 9 | Health back from thrown crits and headshots |
| Accelerated Toxin Absorption | 
|
Cool 9 | Strong attacks and throws on poisoned enemies deal a burst of Poison |
| Corrosion | 
|
Cool 9 | Poison works on mechs, robots, drones and turrets |
| Ninjutsu | 
|
Cool 15 | Sprint while crouched |
| Creeping Death | 
|
Cool 15 | Health, Stamina and speed from kills while hidden |
| Vanishing Act | 
|
Cool 15 | Optical Camo turns on while crouch-sprinting |
| Juggler | 
|
Cool 15 | Thrown headshots and crits return the weapon at once |
| Sleight Of Hand | 
|
Cool 15 | Crit Damage stacks each time Juggler triggers |
| Finisher: Act Of Mercy | 
|
Cool 15 | A thrown weapon Finisher that heals |
| Pay It Forward | 
|
Cool 15 | Big melee hit after picking up a thrown blade |
| Pounce | 
|
Cool 15 | Finishers from range after a throw |
| Style Over Substance | 
|
Cool 20 | Guaranteed crits when throwing on the move |
| Slippery | 
|
Reflexes 4 | Harder to hit while moving fast |
| Dash | 
|
Reflexes 9 | Unlocks the Dash and makes it cheaper |
| Air Dash | 
|
Reflexes 15 | Dash in midair |
| All Things Cyber | 
|
Technical Ability 9 | Stronger cyberware stats |
| License To Chrome | 
|
Technical Ability 15 | Stronger cyberware, more armor and a Skeleton slot |
| Ambidextrous | 
|
Technical Ability 15 | A second Hands cyberware slot |
| Edgerunner | Technical Ability 20 | Cyberware past the capacity limit for a small Health cost |
| Name | Image | Slot | Effect |
|---|---|---|---|
| Black Mamba | 
|
Circulatory System | More damage against poisoned enemies |
| Kerenzikov Boost System | 
|
Frontal Cortex | Stronger Kerenzikov with free shooting Stamina |
| Mechatronic Core | 
|
Frontal Cortex | More damage against drones, robots and mechs |
| Handle Wrap | 
|
Hands | More crit chance with throwables |
| Shock Absorber | 
|
Hands | Less recoil |
| Optical Camo | 
|
Integumentary System | Near invisibility for a few seconds |
| Defenzikov | 
|
Integumentary System | Mitigation after Kerenzikov ends |
| Kerenzikov | 
|
Nervous System | Slows time when aiming during a slide or dodge |
| Stabber | 
|
Nervous System | More crit chance with Blades and throwables |
| Militech Apogee Sandevistan | Operating System | Slows time by 85% with crit bonuses | |
| Dense Marrow | 
|
Skeleton | More melee damage |
| Spring Joints | 
|
Skeleton | Stronger Mitigation |
| Name | Image | Effect |
|---|---|---|
| Zero-G | 
|
Longer throws on a straight path |
| Slice 'Em Up | 
|
Enemies are easier to finish after a kill |
| Bleedout | 
|
Bleeding damage can crit |
Notes
- Blue Fang is the Iconic variant of the Neurotoxin Knife. Its thrown hits stun the target, and outside combat the stun is instant.
- Blue Fang is sold by the melee weapon vendor in Jackson Plains, in the Badlands.
Weapon Categories
All Melee Weapons
Every melee weapon is listed below. The Iconic weapons come first, then the standard ones.
Iconic Melee Weapons
| Name | Image | Weapon | Headshot | Armor Pen | Location |
|---|---|---|---|---|---|
| Agaou | 
|
Axe | +125% | 25% | Dogtown |
| BFC 9000 | 
|
One-Handed Club | Rancho Coronado | ||
| Baby Boomer | 
|
Two-Handed Club | 25% | ||
| Baseball Bat x-MOD2 | 
|
Two-Handed Club | Dogtown | ||
| Black Unicorn | 
|
Katana | 25% | ||
| Blue Fang | 
|
Knife | +150% | Badlands South | |
| Butcher's Cleaver | 
|
Knife | 25% | Coastview | |
| Byakko | 
|
Katana | 25% | Little China | |
| Caretaker's Spade | 
|
Hammer | 25% | Corpo Plaza | |
| Claw x-MOD2 | 
|
Axe | |||
| Cocktail Stick | 
|
Katana | 25% | Japantown | |
| Cottonmouth | 
|
One-Handed Club | 25% | Japantown | |
| Crowbar | 
|
One-Handed Club | |||
| Cut-o-Matic x-MOD2 | 
|
Chainsword | Dogtown | ||
| Errata | 
|
Katana | 25% | Arroyo | |
| Fang | 
|
Knife | +50% | ||
| Gold-Plated Baseball Bat | 
|
Two-Handed Club | 25% | North Oak | |
| Gwynbleidd | 
|
Sword | |||
| Headhunter | 
|
Knife | +150% | West Wind Estate | |
| Jinchu-Maru | 
|
Katana | 25% | Japantown | |
| Murphy's Law | 
|
One-handed Club | 50% | Dogtown | |
| Nehan | 
|
Knife | +150% | Arasaka Waterfront | |
| Sasquatch's Hammer | 
|
Hammer | 75% | Coastview | |
| Satori | 
|
Katana | 25% | Arasaka Waterfront | |
| Scalpel | 
|
Katana | 25% | Northside | |
| Sir John Phallustiff | 
|
Blunt | 25% | Kabuki | |
| Stinger | 
|
Knife | +150% | Badlands East | |
| Tinker Bell | 
|
One-Handed Club | 50% | Badlands East | |
| Tsumetogi | 
|
Katana | 25% | Japantown | |
| Volkodav | 
|
Machete | 25% | Dogtown |
Standard Melee Weapons
| Name | Image | Weapon | Headshot | Armor Pen | Location |
|---|---|---|---|---|---|
| Baseball Bat | 
|
Two-Handed Club | 25% | ||
| Chef's Knife | 
|
Knife | +150% | ||
| Claw | 
|
Axe | +125% | 25% | |
| Cut-O-Matic | 
|
Chainsword | 50% | ||
| Electric Baton Alpha | 
|
One-Handed Club | Rancho Coronado | ||
| Electric Baton Beta | 
|
One-Handed Club | 50% | ||
| Electric Baton Gamma | 
|
One-Handed Club | 50% | ||
| Hammer | 
|
Hammer | 25% | ||
| Kaiken | 
|
Knife | +150% | ||
| Kanabo | 
|
Two-Handed Club | 25% | ||
| Katana | 
|
Katana | 25% | ||
| Knife | 
|
Knife | +200% | ||
| Kukri | 
|
Machete | 25% | ||
| Machete | 
|
Machete | 25% | ||
| Neurotoxin Knife | 
|
Knife | +150% | ||
| Punknife | 
|
Knife | +150% | ||
| Razor | 
|
Machete | 25% | ||
| Steel Pipe | 
|
One-Handed Club | 25% | ||
| Tire Iron | 
|
One-Handed Club | 25% | ||
| Tomahawk | 
|
Axe | +125% | 25% |